Cayla Bensman had 21 points, Natalie Billing 17 and Erica Huber 15 as Anna defeated Columbus Africentric 67-49 on Saturday.
The win marks the second state title for Anna (26-4) in the past three years and third overall (2013, 2011, 1981). The Rockets also own a runner-up trophy from 2012.
It was sweet revenge for Anna against Africentric (22-6), which last year won its third title in six years with a 70-66 overtime win to snap the Rockets' 50-game winning streak.
Africentric (22-6) reduced a 13-point halftime deficit to 36-28 early in the third period but Anna pushed the lead to 50-34 at the end of the quarter on an inbounds pass to Natalie Billing, the third such play for the Rockets in the game.
Marley Hill, the Associated Press co-player of the year for Division III, had 19 points, 13 rebounds and eight blocks for Africentric.
In the Division IV title game, Darian Rose scored 19 points to lead Fort Loramie past Berlin Hiland 57-42.
The win marks the first state title for Fort Loramie (27-3) in seven state appearances. The Redskins have made it to the state tournament three of the past four years (2013, 11,10) and brought home runner-up trophies in 2011 and 1997.
Junior Renae Meyer also contributed a double-double of 10 points and 11 rebounds for the Redskins.
Berlin Hiland (26-4) finished as the state runner-up for the fourth time in the last five years.
Kettering Fairmont won their first title after coming up short in four previous trips to the final four, edging two-time defending champion Twinsburg 52-48 for the Division I crown.
It was the third consecutive year the DI championship game featured Kettering Fairmont and Twinsburg. Fairmont finishes 27-1, while Twinsburg finished 29-1.
For the fifth year in a row, Shaker Heights Hathaway Brown claimed the Division II state championship, defeating Millersburg West Holmes 56-44 in a championship game rematch from a year ago.
The championship streak marks the only time in OHSAA basketball history, boys or girls, that a team has won five straight titles. The Blazers have played in every championship game from 2007-13, finishing as runner-up in 2007 and 2008 before beginning their championship run.
Hathaway Brown (23-6) was led by Nia Marshall, who recorded a double-double with 17 points and 18 rebounds against West Holmes (28-2). Marshall’s 18 rebounds sets a new Division II championship game record, breaking the previous record of 16 set a decade earlier against West Holmes by Jannon Roland from Urbana.